HIGHER diet-induced intestine microbiota scores in NHANES 2011–2018 have been related to decrease gynecologic most cancers odds in all U.S. females.
Food regimen Induced Intestine Microbiota Rating and Most cancers Danger
Researchers evaluated whether or not the eating regimen induced intestine microbiota (DI-GM) rating, a dietary index designed to replicate meals decisions that help microbial well being, was related to gynecologic most cancers (GC) threat in U.S. ladies. Utilizing The U.S. Nationwide Well being and Diet Examination Survey (NHANES) 2011–2018, the evaluation included 8,512 grownup ladies aged 20 years and older.
The DI-GM rating was derived from consumption of 14 meals teams categorized as useful or dangerous to intestine microbial well being. Increased scores indicated stronger adherence to a microbiota-friendly eating regimen sample, reflecting higher consumption of meals anticipated to help microbial range and short-chain fatty acid manufacturing.
Increased Scores Linked to Decrease Gynecologic Most cancers Odds
Girls with gynecologic most cancers had considerably decrease DI-GM scores than these with out the situation (imply 4.7 versus 5.0). In multivariable, survey-weighted logistic regression fashions adjusted for covariates, every one-unit improve in DI-GM rating was related to decrease odds of gynecologic most cancers (adjusted OR: 0.92; 95% CI: 0.87–0.98).
When evaluating broader rating teams, individuals with DI-GM scores of 6 or larger had 27% decrease odds of gynecologic most cancers versus these scoring 0–3. The useful element of the DI-GM rating was additionally independently related to decrease GC threat, suggesting that meals supporting microbial well being could also be driving the noticed relationship. Stratified analyses didn’t present vital impact modification, indicating the affiliation was broadly constant throughout subgroups evaluated.
Medical Takeaway for Girls’s Well being
These findings help the idea that microbiota-friendly dietary patterns could also be linked to diminished gynecologic most cancers threat at a inhabitants stage. Whereas the examine design doesn’t set up causality, it strengthens the rationale for contemplating dietary high quality by a intestine microbiota lens when discussing long-term threat discount methods with sufferers, alongside established screening and prevention approaches.
Reference: Yang Y et al. Dietary patterns linked to intestine microbiota and their affiliation with gynecologic cancers: NHANES 2011–2018. Most cancers Causes Management. 2026;37:34.
