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A CT scan enables detection and treatment of the common cause of high blood pressure.

Health & FitnessA CT scan enables detection and treatment of the common cause of high blood pressure.

Doctors at Queen Mary University of London and Barts Hospital and Cambridge University Hospital have conducted research using a new type of CT scan to illuminate tiny nodules in hormone glands. Treatment of high blood pressure By removing them. Nodules are discovered in one in twenty hypertensive patients.

The research, published today in Nature Medicine, solves a 60-year-old problem of how to detect hormone-producing nodules without a difficult catheter study that is available in only a handful of hospitals, and often fails. Research has also found that, when combined with a urine test, the scan detects a group of patients who come out of all their comorbidities. Blood pressure medications after treatment.

Also read: High Blood Pressure: Simple Ways to Control Blood Pressure During Cold Wave

128 people took part in a new scan study after doctors discovered their High blood pressure (high blood pressure) was caused by a steroid hormone, aldosterone. Scans show that in two-thirds of patients with elevated aldosterone, it is coming from a benign nodule in just one of the adrenal glands, which can then be safely removed. The scan uses a very short-acting dose of methomidate, a radioactive dye that sticks only to the aldosterone-producing nodule. The scan was as accurate as the old catheter test, but was quick, painless and technically successful in every patient. Until now, the catheter test was unable to predict which patients would be completely cured of high blood pressure after surgical removal of the valve. In contrast, the combination of a ‘hot nodule’ on scan and urine steroid test was detected in 18 of 24 patients who had normalized blood pressure with all their medications.

The study, which involved patients from the Barts Hospital, Cambridge University Hospital, and Guy’s and St Thomas’, and the universities of Glasgow and Birmingham, was supported by a partnership between the National Institute for Health and Care Research (NIHR) and the Medical Research Council (MRC). Funding was provided. Bart’s Charity, and the British Heart Foundation.

Professor Morris Brown, co-senior author of the study and professor of endocrine hypertension at Queen Mary University of London, said: “These aldosterone-producing nodules are very small and easily missed on a routine CT scan. They glow for a few minutes. After our injection, they emerge as a clear cause of high blood pressure, which can often be cured. So far, 99% are difficult to diagnose and lack tests. Never has. Hopefully that’s going to change.”

Professor William Drake, co-senior author of the study and professor of clinical endocrinology at Queen Mary University of London, said: “This study was the culmination of years of hard work and collaboration between centers across the UK. Ground Energy and Drive-In talented research fellows who have selflessly devoted their time and energy during the national pandemic emergency while doing this innovative work. The future of research in this field is in very safe hands.”

In most people with high blood pressure (hypertension), the cause is unknown, and the condition requires lifelong treatment through drugs. Previous research from a group at Queen Mary University discovered that in 5-10 percent of people with high blood pressure, it is caused by a gene mutation in the adrenal gland that results in excess production of the steroid hormone aldosterone. Aldosterone causes the body to retain salt, raising blood pressure. Patients with excessive blood levels of aldosterone are resistant to treatment with commonly used drugs for high blood pressure and are at increased risk of heart attack and stroke.

This story was published without editing the text from a wire agency feed.


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