It is possible that stopping may reduce ovulation Ovarian cancer risk In women who ovulate more frequently during their lifetime.
A new international study published this week in the Journal of the National Cancer Institute provides new insights into possible variations in this relationship between different subtypes of ovarian cancer as well as oral contraceptives, pregnancy and Breastfeeding affects the risk of ovarian cancer. In addition to suppressing ovulation.
Ovarian cancer is one. Extremely deadly A group of diseases with limited treatment options, so understanding its origins and the factors that contribute to disease development are important steps to develop preventive strategies and improve women’s health,” senior author “Studies like this, where researchers from around the world come together and share their data, is critical to achieving these goals.”
An analysis of 21,267 women with ovarian cancer and 26,204 healthy control subjects from 25 studies found that factors that shorten the duration of ovulation—ie, oral contraceptives, pregnancy, and breastfeeding—reduce the risk of cancer and This protective effect was stronger than expected. Suppressing ovulation alone. Findings suggest that these factors contribute to cancer risk in other ways, such as through changes in hormones or inflammation.
The researchers also found significant differences between different subtypes of ovarian cancer. For example, mucinous tumors were associated with factors that suppress ovulation, but not with ovulation duration, another indication that oral contraceptives, pregnancy, and breastfeeding increase cancer risk more than ovulation suppression. is affected.
In contrast, for high-grade serous ovarian cancer, the most common and lethal subtype, the association of oral contraceptives, pregnancy, and breast-feeding was as expected, indicating that these factors are serous via ovulation. Contributes to the risk of ovarian cancer.
“These findings emphasize that ovarian cancer subtypes are distinct diseases with different causes,” Modogno said. “This is important because it will hopefully inspire scientists to explore new hypotheses about how these diseases develop and shed new light on how we can prevent them. Currently, treatment options are limited. , so preventing ovarian cancer is the best hope we have for saving lives.”
This story was published without editing the text from a wire agency feed. Only the title has been changed.